Curis Inc (NAS:CRIS)
$ 3.96 -0.18 (-4.35%) Market Cap: 35.05 Mil Enterprise Value: 15.09 Mil PE Ratio: 0 PB Ratio: 0 GF Score: 48/100
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Curis Inc Virtual KOL Event - Reviewing CA-4948 Clinical Data in NHL & AML/MDS Transcript

Dec 08, 2020 / 01:00PM GMT
Release Date Price: $131 (+354.86%)
James E. Dentzer
Curis, Inc. - President, CEO & Director

Good morning everyone, and welcome to our Virtual Key Opinion Leader call to discuss clinical data on our first-in-class IRAK4 inhibitor, CA-4948. 12 months ago, we outlined our goals for 2020 to provide data updates from both of our ongoing clinical trials of CA-4948. Today, we're excited to provide these updates.

For the NHL study, in a presentation yesterday at ASH, we formally identified our recommended Phase II dose, which has demonstrated tumor reduction in 6 of 7 patients and robust tolerability up to 2 years. All of this in single-agent therapy in a heavily pretreated patient population. These are patients who enrolled in our study after feeling on average 4 prior lines of treatment with other therapies.

In addition, we are especially excited about the identification of 2 new biomarkers, which we expect will help us with patient selection and enrichment as we advance into the combination study of CA-4948 with ibrutinib.

For the AML and MDS study, we are highly encouraged by the data released an hour ago.

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